In addition to the standard amino and thiol terminus modifiers, we have introduced three hydrophilic products. The Amino-Modifier 11 is particularly useful for solution-phase couplings of labels to oligos. It is often found that when using classic amino-modifiers, e.g. amino-C6, a hydrophilic spacer is required. This extends the distance of the label from the oligo. The amino products have this hydrophilicity "built-in" and can therefore be used where hydrophilic linking is needed, but the distance of the label from the oligo requires to remain short. Both the MMT and TFA protected versions are available. Similarly, we also now have a thiol modifier with a hydrophilic linker.
- Amino- & Thiol- Terminus Modifiers
- (Hydrophilic) 5'-TFA-Amino-Modifier-11-CE Phosphoramidite
- 5'-MMT-Amino-Modifier C6-CE Phosphoramidite
- 5'-TFA-Amino-Modifier C6-CE Phosphoramidite
- (Hydrophilic) 5'-MMT-Amino-Modifier-11-CE Phosphoramidite
- 5'-MMT-Amino-Modifier C12-CE Phosphoramidite
- Thioctic Acid NHS Ester
- 5'-Thiol-Modifier C6-CE Phosphoramidite
- Thiol-Modifier C6 S-S CE Phosphoramidite
- Hydrophilic S-Bz TEG-CE Phosphoramidite