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Cell Delivery & Uptake

Lipophilic Modification

5'-Tocopherol-CE Phosphoramidite

(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-(4,8,12-trimethyltridecyl)]- chroman-6-yl-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite

  • Item Number: 2163
  • Formula: C38H67N2O3P
  • Formula Weight: 630.94
  • Unit Weight: 492.68
5'-Tocopherol-CE Phosphoramidite
An extension to our line of hydrophobic modifiers, based on Vitamin E. This is used to introduce tocopherol at the 5'-end of the oligo, either directly on the 5'-OH of the final base or in conjunction with a spacer or linker such as spacer 18 or C6 S-S thiol. The latter will enable the tocopherol to be cleaved via the disulphide bridge, for example once the oligo has been delivered to the cell. To include a C8 spacer natively use 5'-Octyl-tocopherol.
  Pack Size Catalogue No Price Quantity
  100µmol 2163-F100 £85.00
  250mg 2163-B250 £164.00