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Researchers wishing to try out PNA products should consider our PNA Product Bundle - and save 30% on list price.


You can read more about PNA oligos - including the use of PNA linkers - in our Help Centre article: The Flexibility of PNA Synthesis.

PNAs are oligonucleotide analogues in which the standard sugar-phosphate backbone of DNA is substituted by a pseudo-peptide backbone. They were invented in 1991 by a group of scientists at the University of Copenhagen: Prof. Peter E. Nielsen, Prof. Ole Buchardt, Dr. Michael Egholm, and Dr. Rolf H. Berg (PNA Inventor Group). PNAs hybridise strongly and sequence-specifically to complementary DNA or RNA, however they are not degraded by nucleases or proteases. Such properties have made PNA the subject of great scientific interest and synthetic PNA oligomers have numerous identified and proposed applications in molecular biology procedures, diagnostic assays, as well as antisense and anti-gene therapies.

After extensive screening, the benzhydryloxycarbonyl (Bhoc) group was selected as the best choice for protecting the exocyclic amino groups of the nucleobases. This group provides sufficient protection during synthesis, is readily removed under the cleavage conditions, and renders solubility to the monomers. For PNA synthesis, therefore, we provide the four Fmoc/Bhoc monomers and a spacer molecule.

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  2. Fmoc-PNA-T-OH
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    Where different unit prices are given for a pack size, please refer to the minimum quantity required to order at that price (e.g. X5, X10). These are not multi-packs, therefore enter the actual quantity of vials you wish to order.
      Pack Size Catalogue No Price Quantity
      700µmol 5004-F700 £75.00
      500mg 5004-B500 £80.00
      1g 5004-C001X1 £135.00
      1g (Min. Qty. 5) 5004-C001X5 £114.75
      1g (Min. Qty. 10) 5004-C001X10 £108.00
      1g (Min. Qty. 25) 5004-C001X25 £94.50
      1g (Min. Qty. 50) 5004-C001X50 £87.75
     
  4. Fmoc-PNA-A(Bhoc)-OH
  5. View Product Details >
    Where different unit prices are given for a pack size, please refer to the minimum quantity required to order at that price (e.g. X5, X10). These are not multi-packs, therefore enter the actual quantity of vials you wish to order.
      Pack Size Catalogue No Price Quantity
      700µmol 5001-F700 £90.00
      500mg 5001-B500 £90.00
      1g 5001-C001X1 £150.00
      1g (Min. Qty. 5) 5001-C001X5 £127.50
      1g (Min. Qty. 10) 5001-C001X10 £120.00
      1g (Min. Qty. 25) 5001-C001X25 £105.00
      1g (Min. Qty. 50) 5001-C001X50 £97.50
     
  6. Fmoc-PNA-C(Bhoc)-OH
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    Where different unit prices are given for a pack size, please refer to the minimum quantity required to order at that price (e.g. X5, X10). These are not multi-packs, therefore enter the actual quantity of vials you wish to order.
      Pack Size Catalogue No Price Quantity
      700µmol 5002-F700 £90.00
      500mg 5002-B500 £90.00
      1g 5002-C001X1 £150.00
      1g (Min. Qty. 5) 5002-C001X5 £127.50
      1g (Min. Qty. 10) 5002-C001X10 £120.00
      1g (Min. Qty. 25) 5002-C001X25 £105.00
      1g (Min. Qty. 50) 5002-C001X50 £97.50
     
  8. Fmoc-PNA-G(Bhoc)-OH
  9. View Product Details >
    Where different unit prices are given for a pack size, please refer to the minimum quantity required to order at that price (e.g. X5, X10). These are not multi-packs, therefore enter the actual quantity of vials you wish to order.
      Pack Size Catalogue No Price Quantity
      700µmol 5003-F700 £100.00
      500mg 5003-B500 £100.00
      1g 5003-C001X1 £170.00
      1g (Min. Qty. 5) 5003-C001X5 £144.50
      1g (Min. Qty. 10) 5003-C001X10 £136.00
      1g (Min. Qty. 25) 5003-C001X25 £119.00
      1g (Min. Qty. 50) 5003-C001X50 £110.50