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We have recently introduced the 2'-TC RNA monomers that offer reduced cycle times, high percentage full-length product and a simple, one-step cleavage & deprotection step.

We provide the four major base 2'-OTBDMS RNA phosphoramidites with a variety of protecting groups designed to maximise the efficiency of the synthesis and widen the scope for deprotection protocols. The halogenated minor base RNA phosphoramidites (5-I-U and 5-Br-U) are also available. These are particularly useful in cross-linking experiments and x-ray structural studies.

We also provide a range of 2'-OMe RNA phosphoramidites, again with a variety of protecting groups. These products have a variety of uses (see the Knowledge Base for further details).

Note that the analagous RNA CPG supports are also available. These are compatible with all phosphoramidite 2'-protection strategies.

  1. 2'-TC RNA Phosphoramidites
  2. Bz-A TC-RNA CE Phosphoramidite
  3. Ac-C TC-RNA CE Phosphoramidite
  4. iBu-G TC-RNA CE Phosphoramidite
  5. U TC-RNA CE Phosphoramidite
  6. Standard & UltraMILD 2'-OTBDMS Phosphoramidites
  7. Bz-A-CE Phosphoramidite
  8. Pac-A-CE Phosphoramidite
  9. Ac-C-CE Phosphoramidite
  10. iPr-Pac-G-CE Phosphoramidite
  11. dmf-G-CE Phosphoramidite
  12. U-CE Phosphoramidite
  13. 5-I-U-CE Phosphoramidite
  14. 5-Br-U-CE Phosphoramidite
  15. Standard & UltraMILD 2'-OMe Phosphoramidites
  16. 2'-OMe-Bz-A-CE Phosphoramidite
  17. 2'-OMe-Pac-A-CE Phosphoramidite
  18. 2'-OMe-Bz-C-CE Phosphoramidite
  19. 2'-OMe-Ac-C-CE Phosphoramidite
  20. 2'-OMe-dmf-G-CE Phosphoramidite
  21. 2'-OMe-iPr-Pac-G-CE Phosphoramidite
  22. 2'-OMe-U-CE Phosphoramidite
  23. 2'-F "RNA" Phosphoramidites
  24. 2'-F-Ac-dC-CE Phosphoramidite
  25. 2'-F-dU-CE Phosphoramidite