Peptide-Oligonucleotide Hybrids in Antisense Therapy
T.L. Pierce, A.R. White, G.W. Tregear and P.M. Sexton, Mini Reviews in Medicinal Chemistry, 5, 41-55, 2005. Abstract
One promising avenue for the enhancement of oligonucleotide uptake for targetted delivery is via linkage of antisense oligonucleotides to peptide carriers. This review looks at the current status of developments in this area, inlcuding our own OPeC™ technology.