Knowledgebase
Please note that a number of older items have been removed as much of our protocol information is now available in the 2010 Product Guide (select the Product Guide filter on the right to download). Protocol information on products added to our range since that Guide's publication is available here.
Filtered by: Application Notes
- Synthesis of oligonucleotides modified with hydrophilic 5'-linker phosphoramidites for use in post-synthetic labelling in aqueous media 24 Jun 2010 Discussion on the use of our hydrophilic amino- and thiol- modifiers.
- Plant derived cholesterol modifications: Comparative use in oligonucleotide synthesis (Technical Information Sheet) 22 Jun 2010 Protocol details for our cholesterol products.
- Plant Derived Cholesterol Modifications - A Comparison of Commercially Available Cholesterol Phosphoramidites and Solid Supports for use in Oligonucleotide Synthesis of DNA and RNA (TC and TBDMS chemistries) - Full TIDES 2010 Poster (1.5MB) 27 Apr 2010 Poster presented at TIDES 2010 in Boston.
- Plant Derived Cholesterol Modifications - A Comparison of Commercially Available Cholesterol Phosphoramidites and Solid Supports for use in Oligonucleotide Synthesis of DNA and RNA (TC and TBDMS chemistries) - Summary (170KB) 27 Apr 2010 2-Page summary of our TIDES 2010 poster.
- RNA synthesis using 2’-thiomorpholine-4-carbothioate (TC) protection 17 Mar 2010 Protocol guidelines for use of the 2'-thiomorpholine-carbothioate RNA phosphoramidites.
- Synthesis of ferrocene-modified oligonucleotides using a ferrocene-dT phosphoramidite (2167) 24 Nov 2009 Comparison in use of Ferrocene-dT CEPA with other methods for labelling oligos.
- Synthesis of UNA and chimeric UNA/DNA, UNA/DNA/RNA oligonucleotides with unlocked nucleic acids (UNA) 02 Nov 2009 Overview and protocol information
- Alternative catalysis of OPeC™ conjugations 27 Jan 2009 Use of mercaptophenyl acetic acid instead of benzyl mercaptan
- Choosing a SynBase™ Solid Support 23 Jan 2009 Overview of the application of SynBase™ Supports
- Labelling of an oligonucleotide with multiple fluoresceins 06 Feb 2006 Advice on the above.